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Is the bioactivity of phytonutrients enhanced in a food matrix? G. DARLAND. HealthComm
International, Inc., P.O. Box 1729, Gig Harbor, WA 98335.
Twenty-five hundred years ago Hipprocates recommended that “food be thy medicine and medicine be
thy food.” The emergence of the functional food industry has provided this aphorism with even greater
significance. Functional foods not only provide the traditional nutrients but also provide a variety of
phytonutrients which may optimize biochemical function and improve the overall well-being of the
consuming population. In order to provide benefit, phytochemicals must first reach their respective site(s) of
action. Bioavailability is thus crucial to their activity. As key ingredients of foods, cereals can be expected to
contribute in this regard. The central hypothesis in this presentation is that there is an advantage to providing
phytonutrients within a food matrix as a opposed to a capsule or pill. The biochemical mechanisms
contributing to enhanced activity will pertain to nutrient absorption, metabolism and the potential for
synergy between specific phytonutrients. Examples of the above will be derived from the fields of
nutritional and pharmaceutical research.