DOI: 10.1094/CC-83-0152 |  VIEW ARTICLE

Extrusion Conditions Modify Hypocholesterolemic Properties of Wheat Bran Fed to Hamsters.

T. S. Kahlon (1,2), J. de J. Berrios (1), G. E. Smith (1), and J. L. Pan (1). (1) Western Regional Research Center, USDA, Agricultural Research Service, 800 Buchanan Street, Albany, CA 94710. Names are necessary to report factually on available data; however, the USDA neither guarantees nor warrants the standard of the product, and the use of the name by the USDA implies no approval of the product to the exclusion of others that may also be suitable. (2) Corresponding author. Phone: 510-559-5665. Fax: 510-559-5777. E-mail: <tsk@pw.usda.gov> Cereal Chem. 83(2):152-156. Accepted November 8, 2005. This article is in the public domain and not copyrightable. It may be freely reprinted with customary crediting of the source. AACC International, Inc., 2006.

Wheat bran was extruded in a twin-screw extruder at five specific mechanical energy (SME) levels (0.120, 0.177, 0.234, 0.291, and 0.358 kWh/kg, dwb) and the cholesterol-lowering effects were compared with those of unprocessed wheat bran when fed to four-week-old male golden Syrian hamsters (n = 10/treatment) for three weeks. Diets contained 10% total dietary fiber, 10.3% fat, 3% nitrogen, and 0.4% cholesterol. Plasma total cholesterol and very-low-density lipoprotein cholesterol were significantly lower with 0.120 kWh/kg extruded wheat bran diet compared with the unextruded wheat bran control. Total triglycerides were significantly lower with 0.120 and 0.177 kWh/kg wheat bran diets compared with those fed 0.291 and 0.358 kWh/kg extruded wheat bran diets. Cholesterol digestibility, total liver cholesterol, and total liver lipids were significantly lower with all the extruded wheat bran diets compared with the unextruded wheat bran control. Cholesterol digestibility for the 0.291 kWh/kg wheat bran diet was also significantly lower than all other extruded diets. Significantly more sterols were excreted with diets containing 0.291 and 0.358 kWh/kg extruded wheat bran compared with the unextruded wheat bran control. Wheat bran extruded with 0.291 kWh/kg diet resulted in a 13% reduction in plasma cholesterol and a 29% reduction in low-density lipoprotein cholesterol. Considering lowest cholesterol digestibility, significantly higher sterol excretion, desirable plasma lipoprotein cholesterol profile, significantly lower liver weight, total liver lipids, and liver cholesterol, the wheat bran extruded at 0.291 kWh/kg appeared to have the most desirable healthful potential. Data suggest that cholesterol-lowering potential of wheat bran could be enhanced by optimizing the energy input used in the extrusion process.